Motif ID: FOX{F1,F2,J1}.p2

Z-value: 0.932


Transcription factors associated with FOX{F1,F2,J1}.p2:

Gene SymbolEntrez IDGene Name
FOXF1 2294 forkhead box F1
FOXF2 2295 forkhead box F2
FOXJ1 2302 forkhead box J1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXF2chr6_+_1335067-0.253.5e-01Click!
FOXJ1chr17_-_71648965-0.126.7e-01Click!
FOXF1chr16_+_851017340.048.8e-01Click!


Activity profile for motif FOX{F1,F2,J1}.p2.

activity profile for motif FOX{F1,F2,J1}.p2


Sorted Z-values histogram for motif FOX{F1,F2,J1}.p2

Sorted Z-values for motif FOX{F1,F2,J1}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOX{F1,F2,J1}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_150020595 1.184 NM_001122853
NM_133371
MYOZ3

myozenin 3

chr9_+_128764324 1.181 NM_001190728
RALGPS1
Ral GEF with PH domain and SH3 binding motif 1
chr13_-_38462857 1.139 NM_001144033
NM_145286
STOML3

stomatin (EPB72)-like 3

chr6_+_101953581 0.842 NM_001166247
NM_021956
NM_175768
GRIK2


glutamate receptor, ionotropic, kainate 2


chr5_-_36337756 0.794 NM_001161429
NM_145000
RANBP3L

RAN binding protein 3-like

chr8_-_30121741 0.787 NM_001100916
MBOAT4
membrane bound O-acyltransferase domain containing 4
chr11_-_117589283 0.787 NM_153206
AMICA1
adhesion molecule, interacts with CXADR antigen 1
chr8_-_110724594 0.784 NM_001099756
SYBU
syntabulin (syntaxin-interacting)
chr1_+_65503011 0.775 NM_014787
DNAJC6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr11_-_114880275 0.762 NM_001098517
NM_014333
CADM1

cell adhesion molecule 1

chr3_+_46628928 0.733 NM_001195442
LOC100132146
hypothetical LOC100132146
chr6_-_128281434 0.713 NM_001164687
THEMIS
thymocyte selection associated
chr7_+_120752656 0.713 NM_016087
WNT16
wingless-type MMTV integration site family, member 16
chr2_-_218739891 0.713 NM_000634
CXCR1
chemokine (C-X-C motif) receptor 1
chr1_+_24522116 0.709 NM_021180
GRHL3
grainyhead-like 3 (Drosophila)
chr1_+_28134090 0.676 NM_001009568
NM_014474
SMPDL3B

sphingomyelin phosphodiesterase, acid-like 3B

chrX_-_48578878 0.660 NM_013271
PCSK1N
proprotein convertase subtilisin/kexin type 1 inhibitor
chr11_+_124294355 0.647 NM_001037558
HEPN1
hepatocellular carcinoma, down-regulated 1
chr20_-_22514092 0.647 NM_153675
FOXA2
forkhead box A2
chr1_-_150564302 0.638 NM_002016
FLG
filaggrin
chr14_-_20562962 0.624 NM_201538
NM_201539
NM_201540
NM_201541
NDRG2



NDRG family member 2



chr18_+_59374372 0.623 NM_080474
SERPINB12
serpin peptidase inhibitor, clade B (ovalbumin), member 12
chr6_+_101953389 0.616 GRIK2
glutamate receptor, ionotropic, kainate 2
chr1_+_40635058 0.605 NM_001198980
SMAP2
small ArfGAP2
chr1_-_24342158 0.604 NM_021258
IL22RA1
interleukin 22 receptor, alpha 1
chr12_-_14929991 0.602 NM_000900
NM_001190839
MGP

matrix Gla protein

chr5_+_140714951 0.600 NM_018917
NM_032053
PCDHGA4

protocadherin gamma subfamily A, 4

chr18_+_59726183 0.590 SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr10_-_90702490 0.582 NM_001613
ACTA2
actin, alpha 2, smooth muscle, aorta
chr5_-_13997588 0.579 NM_001369
DNAH5
dynein, axonemal, heavy chain 5
chr3_-_191650291 0.577 NM_207316
TMEM207
transmembrane protein 207
chr4_-_21559471 0.576 NM_147182
KCNIP4
Kv channel interacting protein 4
chr15_-_48198697 0.548 NM_024837
ATP8B4
ATPase, class I, type 8B, member 4
chr1_+_150753601 0.542 NM_019060
CRCT1
cysteine-rich C-terminal 1
chr11_-_128242342 0.531 NM_153764
NM_153765
NM_153766
NM_153767
KCNJ1



potassium inwardly-rectifying channel, subfamily J, member 1



chr4_-_123761615 0.527 NM_021803
IL21
interleukin 21
chr18_+_59405513 0.519 NM_012397
SERPINB13
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr1_-_109201228 0.514 NM_152763
AKNAD1
AKNA domain containing 1
chr4_-_107508040 0.511 NM_001195138
LOC100507096
GTPase IMAP family member-like
chr10_-_50066386 0.508 NM_001010863
C10orf128
chromosome 10 open reading frame 128
chr11_-_104274606 0.506 NM_001191016
CASP12
caspase 12 (gene/pseudogene)
chr19_-_53708230 0.489 NM_001080434
LMTK3
lemur tyrosine kinase 3
chr7_-_93041971 0.489 NM_001164737
NM_001742
CALCR

calcitonin receptor

chr5_-_59100194 0.473 NM_001197218
PDE4D
phosphodiesterase 4D, cAMP-specific
chr15_-_68781662 0.470 NM_001008224
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr8_+_31616809 0.469 NM_013962
NRG1
neuregulin 1
chr1_+_205068844 0.469 NM_013371
IL19
interleukin 19
chr4_+_88973144 0.463 NM_001184695
NM_001184696
NM_001184697
NM_020203
MEPE



matrix extracellular phosphoglycoprotein



chr21_+_38550533 0.463 NM_002243
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr11_-_113971607 0.450 FAM55D
family with sequence similarity 55, member D
chr11_-_55942283 0.448 NM_001004744
OR5R1
olfactory receptor, family 5, subfamily R, member 1
chr9_-_21295311 0.446 NM_002169
IFNA5
interferon, alpha 5
chr1_+_151270301 0.444 NM_003125
SPRR1B
small proline-rich protein 1B
chr21_+_38566298 0.441 NM_170737
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr1_-_24067347 0.439 NM_000147
FUCA1
fucosidase, alpha-L- 1, tissue
chr12_-_94914133 0.436 NM_002108
HAL
histidine ammonia-lyase
chr11_-_17147863 0.435 NM_002645
PIK3C2A
phosphoinositide-3-kinase, class 2, alpha polypeptide
chr2_+_38009405 0.431 NM_001170792
FAM82A1
family with sequence similarity 82, member A1
chr9_-_21197141 0.429 NM_002171
IFNA10
interferon, alpha 10
chr7_-_48035169 0.425 NM_001030019
NM_152782
SUN3

Sad1 and UNC84 domain containing 3

chr17_+_69939130 0.425 NM_022036
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr6_-_41823056 0.424 NM_001166424
NM_002630
PGC

progastricsin (pepsinogen C)

chr19_+_17723285 0.421 NM_001161359
NM_015122
FCHO1

FCH domain only 1

chr4_+_47403107 0.419


chr1_+_205344200 0.418 NM_000715
C4BPA
complement component 4 binding protein, alpha
chr3_+_115495522 0.415 NM_173799
TIGIT
T cell immunoreceptor with Ig and ITIM domains
chr5_+_54434230 0.415 NM_006144
GZMA
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
chr15_+_40484249 0.414 NM_173089
NM_173090
CAPN3

calpain 3, (p94)

chr1_+_169421011 0.412 NM_001460
FMO2
flavin containing monooxygenase 2 (non-functional)
chr15_-_74139123 0.412 NRG4
neuregulin 4
chr8_-_81155564 0.410 NM_001025252
TPD52
tumor protein D52
chr15_-_77994652 0.404 NM_001100879
ST20
suppressor of tumorigenicity 20
chr7_+_142178743 0.402 NM_002770
PRSS2
protease, serine, 2 (trypsin 2)
chr11_+_55407348 0.398 NM_032681
SPRYD5
SPRY domain containing 5
chr19_-_47638890 0.390 NM_198477
CXCL17
chemokine (C-X-C motif) ligand 17
chr10_-_70846573 0.387 NM_001057
TACR2
tachykinin receptor 2
chr8_+_128497038 0.385 NM_001159542
POU5F1B
POU class 5 homeobox 1B
chr19_+_46390916 0.380 NM_030622
CYP2S1
cytochrome P450, family 2, subfamily S, polypeptide 1
chr8_+_75899326 0.376 NM_015886
PI15
peptidase inhibitor 15
chr12_+_52665196 0.368 NM_017409
HOXC10
homeobox C10
chr12_-_51065629 0.368 NM_033045
KRT84
keratin 84
chr8_-_70909754 0.361 NM_030958
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr22_-_31732648 0.360 NM_003490
NM_133633
SYN3

synapsin III

chr1_+_170656450 0.352 NM_139240
C1orf105
chromosome 1 open reading frame 105
chr4_+_15038726 0.352 NM_031911
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr14_+_31868229 0.351 NM_004274
AKAP6
A kinase (PRKA) anchor protein 6
chr10_+_90511142 0.350 NM_001102469
LIPN
lipase, family member N
chr17_-_37196463 0.350 NM_002230
NM_021991
JUP

junction plakoglobin

chr4_-_82612049 0.348 NM_152545
RASGEF1B
RasGEF domain family, member 1B
chr10_+_35524835 0.345 NM_182721
NM_182722
NM_182723
NM_182724
NM_182725
CREM




cAMP responsive element modulator




chr1_+_92190296 0.345 NM_001726
BRDT
bromodomain, testis-specific
chr15_+_56217686 0.344 NM_020980
AQP9
aquaporin 9
chr5_+_132176921 0.340 NM_175873
ANKRD43
ankyrin repeat domain 43
chr21_+_38550739 0.339 NM_170736
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr2_-_21084077 0.337 APOB
apolipoprotein B (including Ag(x) antigen)
chr4_+_100957003 0.337 NM_014395
DAPP1
dual adaptor of phosphotyrosine and 3-phosphoinositides
chr3_-_39296483 0.331 NM_001337
CX3CR1
chemokine (C-X3-C motif) receptor 1
chr22_+_43527101 0.331 NM_001017526
NM_001198726
NM_181335
ARHGAP8


Rho GTPase activating protein 8


chr18_-_72973750 0.329 NM_001025100
NM_001025101
MBP

myelin basic protein

chr2_+_204440753 0.329 NM_001037631
NM_005214
CTLA4

cytotoxic T-lymphocyte-associated protein 4

chr1_+_32512298 0.328 NM_001042771
LCK
lymphocyte-specific protein tyrosine kinase
chr10_+_95362334 0.327 NM_006204
PDE6C
phosphodiesterase 6C, cGMP-specific, cone, alpha prime
chr10_+_114144512 0.326 ACSL5
acyl-CoA synthetase long-chain family member 5
chr2_+_88966170 0.325


chr4_-_100575313 0.321 NM_001166504
NM_000673
ADH7

alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide

chr8_-_6901661 0.321 NM_021010
DEFA5
defensin, alpha 5, Paneth cell-specific
chr11_-_113971681 0.319 NM_001077639
NM_017678
FAM55D

family with sequence similarity 55, member D

chr11_-_26550243 0.319 NM_001135091
NM_001135092
NM_145650
MUC15


mucin 15, cell surface associated


chr10_+_51219558 0.316 NM_002443
NM_138634
MSMB

microseminoprotein, beta-

chr15_-_38185578 0.316 NM_001003942
NM_001003943
BMF

Bcl2 modifying factor

chr8_+_23483422 0.314 SLC25A37
solute carrier family 25, member 37
chr8_-_27997306 0.312 NM_001010906
C8orf80
chromosome 8 open reading frame 80
chr10_-_91395194 0.310 NM_148977
PANK1
pantothenate kinase 1
chr2_-_36929520 0.310 STRN
striatin, calmodulin binding protein
chr15_-_38953628 0.308 NM_133639
RHOV
ras homolog gene family, member V
chr3_+_108578877 0.308 NM_032600
CCDC54
coiled-coil domain containing 54
chr17_-_36403910 0.308 NM_033185
KRTAP3-3
keratin associated protein 3-3
chr6_+_62341966 0.308 NM_001190706
MTRNR2L9
MT-RNR2-like 9
chr2_-_165133239 0.303 GRB14
growth factor receptor-bound protein 14
chr6_-_56824672 0.300 DST
dystonin
chr6_-_76259976 0.299 NM_015687
FILIP1
filamin A interacting protein 1
chr15_+_46271158 0.299 NM_001145668
CTXN2
SLC12A1
cortexin 2
solute carrier family 12 (sodium/potassium/chloride transporters), member 1
chr9_+_135277264 0.297 ADAMTS13
ADAM metallopeptidase with thrombospondin type 1 motif, 13
chr2_+_11591692 0.297 NM_014668
GREB1
growth regulation by estrogen in breast cancer 1
chr16_-_66590856 0.296 NM_022355
DPEP2
dipeptidase 2
chr6_+_64403668 0.296 PHF3
PHD finger protein 3
chr7_-_83108682 0.296 NM_001178129
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr2_-_180319013 0.295 NM_001113397
ZNF385B
zinc finger protein 385B
chr18_-_3864252 0.295 DLGAP1
discs, large (Drosophila) homolog-associated protein 1
chr8_+_133948384 0.292 NM_003235
TG
thyroglobulin
chr4_-_82611995 0.292 RASGEF1B
RasGEF domain family, member 1B
chr8_+_100025806 0.291 NM_001142462
NM_053001
OSR2

odd-skipped related 2 (Drosophila)

chr8_-_19584373 0.291 NM_018371
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr5_-_76970129 0.290 OTP
orthopedia homeobox
chr2_-_135498716 0.289 NM_001018046
NM_025052
YSK4

YSK4 Sps1/Ste20-related kinase homolog (S. cerevisiae)

chr9_-_76692455 0.288 NM_001177310
TRPM6
transient receptor potential cation channel, subfamily M, member 6
chr6_-_52217185 0.287 NM_052872
IL17F
interleukin 17F
chr5_-_20024050 0.286 NM_001167667
NM_004934
CDH18

cadherin 18, type 2

chr13_-_101852028 0.283 NM_175929
FGF14
fibroblast growth factor 14
chr11_+_6216905 0.283 NM_001037329
CNGA4
cyclic nucleotide gated channel alpha 4
chr18_-_50777634 0.283 NM_025214
CCDC68
coiled-coil domain containing 68
chr16_-_11282595 0.281 NM_002761
PRM1
protamine 1
chr17_+_11726943 0.281 NM_004662
DNAH9
dynein, axonemal, heavy chain 9
chr9_-_205892 0.280 NM_152569
C9orf66
chromosome 9 open reading frame 66
chr6_-_89984214 0.278 NM_002042
GABRR1
gamma-aminobutyric acid (GABA) receptor, rho 1
chr1_-_116185215 0.276 NM_005599
NHLH2
nescient helix loop helix 2
chr19_+_18069596 0.276 NM_015016
MAST3
microtubule associated serine/threonine kinase 3
chr20_+_35266581 0.275 RPN2
ribophorin II
chr15_+_72694387 0.275 NM_001130028
CLK3
CDC-like kinase 3
chr7_+_142053693 0.274 NM_001190487
MTRNR2L6
MT-RNR2-like 6
chr15_+_74139325 0.273 NM_152335
C15orf27
chromosome 15 open reading frame 27
chr1_+_205736095 0.273 NM_000573
NM_000651
CR1

complement component (3b/4b) receptor 1 (Knops blood group)

chr9_-_76692829 0.270 NM_017662
TRPM6
transient receptor potential cation channel, subfamily M, member 6
chr5_-_58607673 0.270 NM_001197220
PDE4D
phosphodiesterase 4D, cAMP-specific
chr11_-_64484184 0.269 NM_001037225
C11orf85
chromosome 11 open reading frame 85
chr11_+_48194937 0.269 NM_001005470
OR4B1
olfactory receptor, family 4, subfamily B, member 1
chr3_-_114221174 0.269 C3orf17
chromosome 3 open reading frame 17
chr16_+_716936 0.265 NM_207112
NM_032304
HAGHL

hydroxyacylglutathione hydrolase-like

chr19_-_12802206 0.264 NM_001080997
RTBDN
retbindin
chr19_-_14030970 0.262 NM_001145028
PALM3
paralemmin 3
chr1_+_149877955 0.262 SNX27
sorting nexin family member 27
chr11_-_72063059 0.261 NM_002599
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr2_-_162717159 0.260 NM_002054
GCG
glucagon
chr11_-_117305277 0.259 NM_001077263
TMPRSS13
transmembrane protease, serine 13
chr10_-_93992982 0.259 NM_001178137
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr12_-_15265490 0.258 NM_001190726
NM_032918
RERG

RAS-like, estrogen-regulated, growth inhibitor

chr3_-_114221204 0.257 NM_015412
C3orf17
chromosome 3 open reading frame 17
chr12_+_53178834 0.257 NM_001184976
NCKAP1L
NCK-associated protein 1-like
chr5_-_137882303 0.256 ETF1
eukaryotic translation termination factor 1
chr14_-_20636568 0.253 NM_016423
ZNF219
zinc finger protein 219
chr1_+_81544432 0.253 LPHN2
latrophilin 2
chr9_+_135276940 0.253 NM_139025
NM_139026
NM_139027
ADAMTS13


ADAM metallopeptidase with thrombospondin type 1 motif, 13


chr7_+_142768916 0.252 ZYX
zyxin
chr4_+_172971149 0.251 NM_001034845
GALNTL6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6
chr7_+_99263571 0.251 NM_022820
NM_057095
NM_057096
CYP3A43


cytochrome P450, family 3, subfamily A, polypeptide 43


chr13_-_48873735 0.249 NM_030925
CAB39L
calcium binding protein 39-like
chr10_+_118177371 0.248 NM_001011709
PNLIPRP3
pancreatic lipase-related protein 3
chr12_-_10142779 0.248 NM_016511
CLEC1A
C-type lectin domain family 1, member A
chr1_+_92318449 0.247 NM_183242
BTBD8
BTB (POZ) domain containing 8
chr1_-_205161821 0.247 NM_001193338
NM_001142473
NM_005449
FAIM3


Fas apoptotic inhibitory molecule 3


chr11_-_8695974 0.246 ST5
suppression of tumorigenicity 5
chr10_+_60606352 0.245 NM_032439
PHYHIPL
phytanoyl-CoA 2-hydroxylase interacting protein-like
chr9_+_6231677 0.244 NM_033439
IL33
interleukin 33
chr3_-_12561962 0.243 NM_001195279
LOC100129480
hypothetical protein LOC100129480
chr4_-_77042599 0.243 NM_006239
PPEF2
protein phosphatase, EF-hand calcium binding domain 2
chr15_+_83467295 0.242 PDE8A
phosphodiesterase 8A
chr12_+_120055013 0.240 NM_002562
P2RX7
purinergic receptor P2X, ligand-gated ion channel, 7
chr1_+_210864411 0.240 NM_153606
FAM71A
family with sequence similarity 71, member A
chr17_-_36276987 0.240 NM_000223
KRT12
keratin 12
chr18_+_53170718 0.239 NM_015879
ST8SIA3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr17_-_36475652 0.238 NM_033184
KRTAP2-4
keratin associated protein 2-4
chr1_-_205272619 0.237 NM_001083924
NM_023938
C1orf116

chromosome 1 open reading frame 116

chr4_+_38740246 0.237 NM_015990
NM_199039
KLHL5

kelch-like 5 (Drosophila)

chr11_-_27679617 0.236 NM_170733
BDNF
brain-derived neurotrophic factor
chr3_+_160473784 0.236 SCHIP1
schwannomin interacting protein 1
chr15_+_60146467 0.236 NM_207322
C2CD4A
C2 calcium-dependent domain containing 4A
chr19_+_54723044 0.236 RCN3
reticulocalbin 3, EF-hand calcium binding domain
chr1_-_229627412 0.235 NM_022051
EGLN1
egl nine homolog 1 (C. elegans)
chr7_-_107230867 0.233 NM_000111
SLC26A3
solute carrier family 26, member 3
chr9_-_124981125 0.231 STRBP
spermatid perinuclear RNA binding protein

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.27 2.96e-04 GO:0005886 plasma membrane
1.27 4.02e-04 GO:0071944 cell periphery
1.36 6.20e-03 GO:0005576 extracellular region
1.48 3.09e-02 GO:0044421 extracellular region part

Nothing significant found in function category.